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Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages

The current situation of the Covid-19 pandemic is indicated by a huge number of infections, high lethality, and rapid spread. These circumstances have stopped the activity of almost the entire world, affecting severely the global economy. A rapid diagnosis of the Covid-19 and a generalized testing p...

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Detalles Bibliográficos
Autores principales: Pérez-López, Briza, Mir, Mònica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713573/
https://www.ncbi.nlm.nih.gov/pubmed/33592692
http://dx.doi.org/10.1016/j.talanta.2020.121898
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author Pérez-López, Briza
Mir, Mònica
author_facet Pérez-López, Briza
Mir, Mònica
author_sort Pérez-López, Briza
collection PubMed
description The current situation of the Covid-19 pandemic is indicated by a huge number of infections, high lethality, and rapid spread. These circumstances have stopped the activity of almost the entire world, affecting severely the global economy. A rapid diagnosis of the Covid-19 and a generalized testing protocol is essential to fight against the pandemic and to maintain health control in the population. Principal biosensing and diagnostic technologies used to monitor the spread of the SARS-CoV-2 are based on specific genomic analysis and rapid immune tests, both with different technology platforms that include advantages and disadvantages. Most of the in vitro diagnosis companies are competing to be the first on validating under different regulations their technology for placing their platforms for Covid-19 detection as fast as possible in this big international market. A comprehensive analysis of the commercialized technologies for the genomic based sensing and the antibody/antigen detection methods devoted to Covid-19 diagnosis is described in this review, which have been detailed and listed under different countries regulations. The effectiveness of the described technologies throughout the different stages of the disease and a critical comparison of the emerging technologies in the market to counterattack this pandemic have been discussed.
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spelling pubmed-77135732020-12-04 Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages Pérez-López, Briza Mir, Mònica Talanta Review The current situation of the Covid-19 pandemic is indicated by a huge number of infections, high lethality, and rapid spread. These circumstances have stopped the activity of almost the entire world, affecting severely the global economy. A rapid diagnosis of the Covid-19 and a generalized testing protocol is essential to fight against the pandemic and to maintain health control in the population. Principal biosensing and diagnostic technologies used to monitor the spread of the SARS-CoV-2 are based on specific genomic analysis and rapid immune tests, both with different technology platforms that include advantages and disadvantages. Most of the in vitro diagnosis companies are competing to be the first on validating under different regulations their technology for placing their platforms for Covid-19 detection as fast as possible in this big international market. A comprehensive analysis of the commercialized technologies for the genomic based sensing and the antibody/antigen detection methods devoted to Covid-19 diagnosis is described in this review, which have been detailed and listed under different countries regulations. The effectiveness of the described technologies throughout the different stages of the disease and a critical comparison of the emerging technologies in the market to counterattack this pandemic have been discussed. Elsevier B.V. 2021-04-01 2020-12-03 /pmc/articles/PMC7713573/ /pubmed/33592692 http://dx.doi.org/10.1016/j.talanta.2020.121898 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Pérez-López, Briza
Mir, Mònica
Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages
title Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages
title_full Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages
title_fullStr Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages
title_full_unstemmed Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages
title_short Commercialized diagnostic technologies to combat SARS-CoV2: Advantages and disadvantages
title_sort commercialized diagnostic technologies to combat sars-cov2: advantages and disadvantages
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713573/
https://www.ncbi.nlm.nih.gov/pubmed/33592692
http://dx.doi.org/10.1016/j.talanta.2020.121898
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