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Anti-Toxoplasma gondii activity of 5-oxo-hexahydroquinoline derivatives: synthesis, in vitro and in vivo evaluations, and molecular docking analysis

BACKGROUND AND PURPOSE: The aim of this study was to evaluate the in vitro and in vivo anti-Toxoplasma gondii (T. gondii) effect of 5-oxo-hexahydroquinoline compounds. Moreover, molecular docking study of the compounds into the active site of enoyl-acyl carrier protein reductase (ENR) as a necessary...

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Detalles Bibliográficos
Autores principales:	Zahedi, Mohammadsaeid, Asgari, Qasem, Badakhshan, Fatemeh, Sakhteman, Amirhossein, Ranjbar, Sara, Khoshneviszadeh, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714012/ https://www.ncbi.nlm.nih.gov/pubmed/33312215 http://dx.doi.org/10.4103/1735-5362.293515

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