Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2

Tumor necrosis factor-alpha (TNF-α) plays an important pathogenic role in cardiac hypertrophy and heart failure (HF); however, anti-TNF is paradoxically negative in clinical trials and even worsens HF, indicating a possible protective role of TNF-α in HF. TNF-α exists in transmembrane (tmTNF-α) and...

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Detalles Bibliográficos
Autores principales: Miao, Kun, Zhou, Ling, Ba, Hongping, Li, Chenxi, Gu, Haiyan, Yin, Bingjiao, Wang, Jing, Yang, Xiang-ping, Li, Zhuoya, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714153/
https://www.ncbi.nlm.nih.gov/pubmed/33270628
http://dx.doi.org/10.1371/journal.pbio.3000967

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