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Disturbed flow–induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis
Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the expression of leukocyte adhesion molecules and ch...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714404/ https://www.ncbi.nlm.nih.gov/pubmed/33268595 http://dx.doi.org/10.1172/jci.insight.140485 |