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Adipocyte ADAM17 plays a limited role in metabolic inflammation

The role of ADAM17, its substrates, and its natural inhibitor has been well studied in the context of inflammation, including metabolic inflammation, with mixed results. Previous studies examining global Adam17 knockdown models and ADAM17 inhibition using overexpression of endogenous ADAM17 inhibito...

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Detalles Bibliográficos
Autores principales: Lownik, Joseph C., Farrar, Jared S., Pearce, Janina V., Celi, Francesco S., Martin, Rebecca K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714430/
https://www.ncbi.nlm.nih.gov/pubmed/32892692
http://dx.doi.org/10.1080/21623945.2020.1814544