RNA polymerase II-binding aptamers in human ACRO1 satellites disrupt transcription in cis

Transcription elongation is a highly regulated process affected by many proteins, RNAs and the underlying DNA. Here we show that the nascent RNA can interfere with transcription in human cells, extending our previous findings from bacteria and yeast. We identified a variety of Pol II-binding aptamer...

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Detalles Bibliográficos
Autores principales: Boots, Jennifer L., von Pelchrzim, Frederike, Weiss, Adam, Zimmermann, Bob, Friesacher, Theres, Radtke, Maximilian, Żywicki, Marek, Chen, Doris, Matylla-Kulińska, Katarzyna, Zagrovic, Bojan, Schroeder, Renée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714431/
https://www.ncbi.nlm.nih.gov/pubmed/32663063
http://dx.doi.org/10.1080/21541264.2020.1790990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714431/
https://www.ncbi.nlm.nih.gov/pubmed/32663063
http://dx.doi.org/10.1080/21541264.2020.1790990

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