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RNA polymerase II-binding aptamers in human ACRO1 satellites disrupt transcription in cis
Transcription elongation is a highly regulated process affected by many proteins, RNAs and the underlying DNA. Here we show that the nascent RNA can interfere with transcription in human cells, extending our previous findings from bacteria and yeast. We identified a variety of Pol II-binding aptamer...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714431/ https://www.ncbi.nlm.nih.gov/pubmed/32663063 http://dx.doi.org/10.1080/21541264.2020.1790990 |