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NK cells in pancreatic cancer demonstrate impaired cytotoxicity and a regulatory IL-10 phenotype
Pancreatic ductal adenocarcinoma (PDAC) is one of the most common tumor subtypes and remains associated with very poor survival. T cell infiltration into tumor tissue is associated with improved clinical outcome but little is known regarding the potential role of NK cells in disease control. Here we...
Autores principales: | Marcon, Francesca, Zuo, Jianmin, Pearce, Hayden, Nicol, Samantha, Margielewska-Davies, Sandra, Farhat, Mustafa, Mahon, Brinder, Middleton, Gary, Brown, Rachel, Roberts, Keith J., Moss, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714501/ https://www.ncbi.nlm.nih.gov/pubmed/33299656 http://dx.doi.org/10.1080/2162402X.2020.1845424 |
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