The era of CFTR modulators: improvements made and remaining challenges

The entry into the clinic of CFTR modulators such as TRIKAFTA has significantly improved life for ∼90% CF patients carrying one or two F508del mutations but challenges remain for rare CFTR mutations and the management of lung infections @SaraOcana1 https://bit.ly/3aRafQF

Detalles Bibliográficos
Autores principales: Cuevas-Ocaña, Sara, Laselva, Onofrio, Avolio, Julie, Nenna, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Expert Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714553/
https://www.ncbi.nlm.nih.gov/pubmed/33304402
http://dx.doi.org/10.1183/20734735.0016-2020
_version_ 1783618767323922432
author Cuevas-Ocaña, Sara
Laselva, Onofrio
Avolio, Julie
Nenna, Raffaella
author_facet Cuevas-Ocaña, Sara
Laselva, Onofrio
Avolio, Julie
Nenna, Raffaella
author_sort Cuevas-Ocaña, Sara
collection PubMed
description The entry into the clinic of CFTR modulators such as TRIKAFTA has significantly improved life for ∼90% CF patients carrying one or two F508del mutations but challenges remain for rare CFTR mutations and the management of lung infections @SaraOcana1 https://bit.ly/3aRafQF
format Online
Article
Text
id pubmed-7714553
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher European Respiratory Society
record_format MEDLINE/PubMed
spelling pubmed-77145532020-12-09 The era of CFTR modulators: improvements made and remaining challenges Cuevas-Ocaña, Sara Laselva, Onofrio Avolio, Julie Nenna, Raffaella Breathe (Sheff) Expert Opinion The entry into the clinic of CFTR modulators such as TRIKAFTA has significantly improved life for ∼90% CF patients carrying one or two F508del mutations but challenges remain for rare CFTR mutations and the management of lung infections @SaraOcana1 https://bit.ly/3aRafQF European Respiratory Society 2020-06 /pmc/articles/PMC7714553/ /pubmed/33304402 http://dx.doi.org/10.1183/20734735.0016-2020 Text en Copyright ©ERS 2020 http://creativecommons.org/licenses/by-nc/4.0/Breathe articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Expert Opinion
Cuevas-Ocaña, Sara
Laselva, Onofrio
Avolio, Julie
Nenna, Raffaella
The era of CFTR modulators: improvements made and remaining challenges
title The era of CFTR modulators: improvements made and remaining challenges
title_full The era of CFTR modulators: improvements made and remaining challenges
title_fullStr The era of CFTR modulators: improvements made and remaining challenges
title_full_unstemmed The era of CFTR modulators: improvements made and remaining challenges
title_short The era of CFTR modulators: improvements made and remaining challenges
title_sort era of cftr modulators: improvements made and remaining challenges
topic Expert Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714553/
https://www.ncbi.nlm.nih.gov/pubmed/33304402
http://dx.doi.org/10.1183/20734735.0016-2020
work_keys_str_mv AT cuevasocanasara theeraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT laselvaonofrio theeraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT avoliojulie theeraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT nennaraffaella theeraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT cuevasocanasara eraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT laselvaonofrio eraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT avoliojulie eraofcftrmodulatorsimprovementsmadeandremainingchallenges
AT nennaraffaella eraofcftrmodulatorsimprovementsmadeandremainingchallenges

Ejemplares similares