Cargando…

Mechanism by which TRAF6 Participates in the Immune Regulation of Autoimmune Diseases and Cancer

Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6), an E3 ubiquitin ligase, is a signal transduction molecule shared by the interleukin-1 receptor (IL-1R)/Toll-like receptor (TLR) family and the TNFR superfamily. TRAF6 has a unique TRAF domain and RING finger domain that mediate intrac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jingjing, Wu, Xinjie, Jiang, Mengyu, Tai, Guixiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714562/ https://www.ncbi.nlm.nih.gov/pubmed/33294443 http://dx.doi.org/10.1155/2020/4607197

Ejemplares similares

Different Activation of TRAF4 and TRAF6 in Inflammatory Bowel Disease
por: Shen, Jun, et al.
Publicado: (2013)

The TRAF6-NFκB signaling pathway in autoimmunity: not just inflammation
por: Thomas, Ranjeny
Publicado: (2005)

TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity
por: Muto, Go, et al.
Publicado: (2013)

The Effect of Different Immunization Cycles of a Recombinant Mucin1-Maltose-Binding Protein Vaccine on T Cell Responses to B16-MUC1 Melanoma in Mice
por: Zhou, Hongyue, et al.
Publicado: (2020)

Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling
por: Arron, Joseph R., et al.
Publicado: (2002)

Up-regulation and Pre-activation of TRAF3 and TRAF5 in Inflammatory Bowel Disease
por: Shen, Jun, et al.
Publicado: (2013)

Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?
por: Petrova, Tsvetana, et al.
Publicado: (2022)

TRAF6 regulates the signaling pathway influencing colorectal cancer function through ubiquitination mechanisms
por: Guangwei, Zhu, et al.
Publicado: (2022)

TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin
por: Luo, Zhongling, et al.
Publicado: (2016)

C-Cbl negatively regulates TRAF6-mediated NF-κB activation by promoting K48-linked polyubiquitination of TRAF6
por: Jang, Hyun-Duk, et al.
Publicado: (2019)

Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-γ
por: Opaluch, Amanda M., et al.
Publicado: (2014)

The relationship between TRAF6 and tumors
por: Li, Jiaoduan, et al.
Publicado: (2020)

Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex
por: Xu, Gang, et al.
Publicado: (2019)

BICP0 Negatively Regulates TRAF6-Mediated NF-κB and Interferon Activation by Promoting K48-Linked Polyubiquitination of TRAF6
por: Cao, Chong, et al.
Publicado: (2020)

The Roles of TRAF3 in Immune Responses
por: Lin, Mengjiao, et al.
Publicado: (2023)

Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome
por: Zhang, Liting, et al.
Publicado: (2018)

Immune Control by TRAF6-Mediated Pathways of Epithelial Cells in the EIME (Epithelial Immune Microenvironment)
por: Dainichi, Teruki, et al.
Publicado: (2019)

TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation
por: Lin, Fang-Tsyr, et al.
Publicado: (2016)

Translation of TRAF1 is regulated by IRES-dependent mechanism and stimulated by vincristine
por: Yang, Lin, et al.
Publicado: (2010)

Roles of TRAF6 in Central Nervous System
por: Dou, Yang, et al.
Publicado: (2018)

Regulation of MiR-146a and TRAF6 in the Diagnose of Lupus Nephritis
por: Zhu, Yunfeng, et al.
Publicado: (2017)

Sestrin2 Regulates Osteoclastogenesis via the p62-TRAF6 Interaction
por: Oh, Sue Young, et al.
Publicado: (2021)

Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung
por: Han, Daehee, et al.
Publicado: (2017)

GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation
por: Zhang, Xuewu, et al.
Publicado: (2017)

TRAF3 regulates the effector function of regulatory T cells and humoral immune responses
por: Chang, Jae-Hoon, et al.
Publicado: (2014)

Rnd3 suppresses endothelial cell pyroptosis in atherosclerosis through regulation of ubiquitination of TRAF6
por: Zhang, Yan, et al.
Publicado: (2023)

Sufu limits sepsis-induced lung inflammation via regulating phase separation of TRAF6
por: Li, Yehua, et al.
Publicado: (2023)

Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR
por: Li, Hanzeng, et al.
Publicado: (2021)

HSV Infection Induces Production of ROS, which Potentiate Signaling from Pattern Recognition Receptors: Role for S-glutathionylation of TRAF3 and 6
por: Gonzalez-Dosal, Regina, et al.
Publicado: (2011)

Comparison of Target Recognition by TRAF1 and TRAF2
por: Kim, Chang Min, et al.
Publicado: (2020)

The N(6)-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response
por: Zong, Xin, et al.
Publicado: (2021)

Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6
por: Min, Yoon, et al.
Publicado: (2016)

TRAF6 Distinctly Regulates Hematopoietic Stem and Progenitors at Different Periods of Development in Mice
por: Kim, Hyekang, et al.
Publicado: (2018)

The Effects of TRAF6 on Growth and Progression in Colorectal Cancer are Regulated by miRNA-140
por: Zhu, Guangwei, et al.
Publicado: (2020)

Correction: GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation
por: Zhang, Xuewu, et al.
Publicado: (2018)

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction
por: Xie, Xiaoping, et al.
Publicado: (2019)

Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6
por: Machado, Fabiana S., et al.
Publicado: (2008)

Native and aspirin-triggered lipoxins control innate immunity by inducing proteasomal degradation of TRAF6
por: Machado, Fabiana S., et al.
Publicado: (2009)

The protease calpain2a limits innate immunity by targeting TRAF6 in teleost fish
por: Chen, Yang, et al.
Publicado: (2023)

(+)-Vitisin A Inhibits Osteoclast Differentiation by Preventing TRAF6 Ubiquitination and TRAF6-TAK1 Formation to Suppress NFATc1 Activation
por: Chiou, Wen-Fei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9dnvoj7esee38iip01lof9b0ri