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The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer

Drug resistance remains a barrier in the clinical treatment of ovarian cancer. Proteasomal and antioxidant activities play important roles in tumor drug resistance, and increasing evidence suggests the existence of an interaction between antioxidant and proteasomal activities. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Deng, Xinyue, Lin, Nan, Fu, Jiaying, Xu, Long, Luo, Haoge, Jin, Yao, Liu, Yanan, Sun, Liankun, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714579/
https://www.ncbi.nlm.nih.gov/pubmed/33294122
http://dx.doi.org/10.1155/2020/4830418