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Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness

Guillain‐Barré syndrome (GBS) is a relatively uncommon post-infectious, immune‐mediated neurologic disorder with an incidence of 0.5-2/100,000. It is usually preceded by an infection that evokes an immune response that cross-reacts with peripheral nerve components via molecular mimicry. The presenta...

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Autores principales: Latif, Azka, Kapoor, Vikas, Sood, Akshat, Thirumalareddy, Joseph, Tauseef, Abubakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714740/
https://www.ncbi.nlm.nih.gov/pubmed/33282578
http://dx.doi.org/10.7759/cureus.11301
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author Latif, Azka
Kapoor, Vikas
Sood, Akshat
Thirumalareddy, Joseph
Tauseef, Abubakar
author_facet Latif, Azka
Kapoor, Vikas
Sood, Akshat
Thirumalareddy, Joseph
Tauseef, Abubakar
author_sort Latif, Azka
collection PubMed
description Guillain‐Barré syndrome (GBS) is a relatively uncommon post-infectious, immune‐mediated neurologic disorder with an incidence of 0.5-2/100,000. It is usually preceded by an infection that evokes an immune response that cross-reacts with peripheral nerve components via molecular mimicry. The presentation of this disorder has several forms, including acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor-sensory axonal neuropathy (AMSAN), and Miller Fisher syndrome (MFS). The case we describe is of a 57-year-old male presenting with sensory features followed by symmetrical ascending paralysis and diagnosed with ASMAN, a recently described subtype of GBS, based on neurological and laboratory findings.
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spelling pubmed-77147402020-12-05 Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness Latif, Azka Kapoor, Vikas Sood, Akshat Thirumalareddy, Joseph Tauseef, Abubakar Cureus Internal Medicine Guillain‐Barré syndrome (GBS) is a relatively uncommon post-infectious, immune‐mediated neurologic disorder with an incidence of 0.5-2/100,000. It is usually preceded by an infection that evokes an immune response that cross-reacts with peripheral nerve components via molecular mimicry. The presentation of this disorder has several forms, including acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor-sensory axonal neuropathy (AMSAN), and Miller Fisher syndrome (MFS). The case we describe is of a 57-year-old male presenting with sensory features followed by symmetrical ascending paralysis and diagnosed with ASMAN, a recently described subtype of GBS, based on neurological and laboratory findings. Cureus 2020-11-02 /pmc/articles/PMC7714740/ /pubmed/33282578 http://dx.doi.org/10.7759/cureus.11301 Text en Copyright © 2020, Latif et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Latif, Azka
Kapoor, Vikas
Sood, Akshat
Thirumalareddy, Joseph
Tauseef, Abubakar
Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness
title Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness
title_full Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness
title_fullStr Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness
title_full_unstemmed Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness
title_short Acute Sensory-Motor Axonal Neuropathy in a 57-Year-Old Male Presenting With Paresthesia and Distal Muscle Weakness
title_sort acute sensory-motor axonal neuropathy in a 57-year-old male presenting with paresthesia and distal muscle weakness
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714740/
https://www.ncbi.nlm.nih.gov/pubmed/33282578
http://dx.doi.org/10.7759/cureus.11301
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