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Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils

Alpha 1 antitrypsin deficiency (AATD) is an autosomal co-dominant disorder characterized by a low level of circulating AAT, which significantly reduces protection for the lower airways against proteolytic burden caused by neutrophils. Neutrophils, which are terminally differentiated innate immune ce...

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Detalles Bibliográficos
Autores principales:	Lee, Jungnam, Lu, Yuanqing, Oshins, Regina, West, Jesse, Moneypenny, Craig G., Han, Kyudong, Brantly, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714766/ https://www.ncbi.nlm.nih.gov/pubmed/33329539 http://dx.doi.org/10.3389/fimmu.2020.574410

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