CD4 and CD8 T Cell Memory Interactions Alter Innate Immunity and Organ Injury in the CLP Sepsis Model

The role of T cell memory in sepsis is poorly understood. Recent work has demonstrated that mice exposed to frequent antigenic stimulation, in contrast to laboratory mice, better recapitulate the human T cell repertoire. This difference may profoundly alter responses to inflammatory insults. We indu...

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Detalles Bibliográficos
Autores principales: Taylor, Matthew D., Fernandes, Tiago D., Kelly, Alexander P., Abraham, Mabel N., Deutschman, Clifford S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715000/
https://www.ncbi.nlm.nih.gov/pubmed/33329524
http://dx.doi.org/10.3389/fimmu.2020.563402

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