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Vascular Smooth Muscle FTO Promotes Aortic Dissecting Aneurysms via m6A Modification of Klf5

Background: Aortic dissecting aneurysm (ADA) represents an aortic remodeling disease with a high mortality rate. Fat mass and obesity-associated protein (FTO) exerts RNA demethylation function to regulate gene expression related to stem cell differentiation, DNA damage repair, and tumorigenesis, but...

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Detalles Bibliográficos
Autores principales:	Ma, Dong, Liu, Xiao, Zhang, Jin-jin, Zhao, Jun-jian, Xiong, Yan-jie, Chang, Quan, Wang, Hong-yan, Su, Peng, Meng, Jia, Zhao, Yong-bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715013/ https://www.ncbi.nlm.nih.gov/pubmed/33330653 http://dx.doi.org/10.3389/fcvm.2020.592550

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