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HER3 Differentiates Basal From Claudin Type Triple Negative Breast Cancer and Contributes to Drug and Microenvironmental Induced Resistance

Triple Negative Breast Cancer (TNBC) is an aggressive form of Breast Cancer (BC). Numerous kinase inhibitors (KI) targeting different pathway nodes have shown limited benefit in the clinical setting. In this study, we aim to characterize the extent of HER3 reliance and to define the effect of Neureg...

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Detalles Bibliográficos
Autores principales: Sinevici, Nicoleta, Ataeinia, Bahar, Zehnder, Veronica, Lin, Kevin, Grove, Lauren, Heidari, Pedram, Mahmood, Umar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715030/
https://www.ncbi.nlm.nih.gov/pubmed/33330026
http://dx.doi.org/10.3389/fonc.2020.554704