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HGG-44. DEFECTS OF MISMATCH REPAIR PROTEINS IN PEDIATRIC HIGH GRADE GLIOMAS

Hetero- and homozygous germline mutations of the mismatch repair genes MLH1, PMS2, MSH2 and MSH6 cause Lynch and constitutional mismatch repair (CMMRD) cancer predisposition syndrome, respectively. Affected CMMRD individuals are at risk to develop a variety of neoplasms including CNS tumors, particu...

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Detalles Bibliográficos
Autores principales:	Haberler, Christine, Muller, Philippe, Müllauer, Leonhard, Peyrl, Andreas, Czech, Thomas, Wimmer, Katharina, Slavc, Irene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	High Grade Glioma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715106/ http://dx.doi.org/10.1093/neuonc/noaa222.325

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