EPEN-31. SINGLE-CELL RNAseq OF CHILDHOOD EPENDYMOMA REVEALS DISTINCT NEOPLASTIC CELL SUBPOPULATIONS THAT IMPACT ETIOLOGY, MOLECULAR CLASSIFICATION AND OUTCOME

Ependymoma (EPN) is a brain tumor commonly presenting in childhood that remains fatal in the majority of children. Intra-tumoral cellular heterogeneity in bulk-tumor samples significantly confounds our understanding of EPN biology, impeding development of effective therapy. We therefore used single-...

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Detalles Bibliográficos
Autores principales: Donson, Andrew, Gillen, Austin, Kent, Riemondy, Gilani, Ahmed, Venkataraman, Sujatha, Sanford, Bridget, Griesinger, Andrea, Amani, Vladimir, Hankinson, Todd, Handler, Michael, Hesselberth, Jay, Vibhakar, Rajeev, Foreman, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Ependymoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715117/
http://dx.doi.org/10.1093/neuonc/noaa222.167

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