IMG-12. CHARACTERISATION OF MODELS OF H3F3A_G34R/V MUTANT PAEDIATRIC GLIOBLASTOMA IN VIVO USING MAGNETIC RESONANCE IMAGING

Approximately 15% of paediatric/young adult cerebral hemispheric glioblastomas (pGBM) harbour G34R/V mutations in H3F3A, encoding the histone H3.3 variant. Development of novel therapeutic interventions demands models that accurately recapitulate this subset of disease and sensitive imaging methods...

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Detalles Bibliográficos
Autores principales: Boult, Jessica, Bjerke, Lynn, Fofana, Mariama, Vinci, Maria, Molinari, Valeria, Mackay, Alan, Temelso, Sara, Box, Gary, Eccles, Suzanne, Carcaboso, Angel, Castro, Maria, Waanders, Angela, Cole, Kristina, Jones, Chris, Robinson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715122/
http://dx.doi.org/10.1093/neuonc/noaa222.347

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