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ETMR-05. SINGLE-CELL RNA-SEQ OF ETMR REVEALS CELL PROGRAMS OF DEVELOPMENTAL HIERARCHY AND CELLULAR DIVERSITY IN THE TUMOR MICROENVIRONMENT

Embryonal tumors with multilayered rosettes (ETMR) are deadly brain malignancies affecting young children. No standard treatment is available and the median survival is less than 12 months. Molecularly, the disease is characterized by the miRNA C19MC cluster amplification, with the expression of mul...

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Detalles Bibliográficos
Autores principales: de Faria, Flavia W, Interlandi, Marta, Moreno, Natalia, Graf, Monika, Melcher, Viktoria, Albert, Thomas K, Kerl, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715162/
http://dx.doi.org/10.1093/neuonc/noaa222.209

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