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ATRT-22. HIGH-THROUGHPUT DRUG SCREENING OF FDA-APPROVED CANCER DRUGS REVEALS POTENTIAL THERAPEUTIC APPROACHES FOR ATYPICAL TERATOID RHABDOID TUMOUR

Atypical teratoid/rhabdoid tumors (ATRT), are the most common brain tumor in children under the age of 1 year with an overall survival of ~17%. Like extracranial rhabdoid tumors, ATRT is exclusively characterized by bi-allelic loss of SMARCB1, a critical subunit of the SWI/SNF chromatin remodeling c...

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Detalles Bibliográficos
Autores principales:	Chong, Wai Chin, Zhukova, Nataliya, Wood, Paul, Downie, Peter A, Cain, Jason E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Atypical Teratoid/Rhabdoid Tumors
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715229/ http://dx.doi.org/10.1093/neuonc/noaa222.021

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