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RARE-08. CYST FLUID CYTOKINES MAY PROMOTE EPITHELIAL-TO-MESENCHYMAL TRANSITION IN PEDIATRIC ADAMANTINOMATOUS CRANIOPHARYNGIOMA
BACKGROUND: Despite poor clinical outcomes, no targeted therapies have been established for the treatment of Adamantinomatous Craniopharyngioma (ACP). The only known genetic aberration is a mutation in CTNNB1 that results in the nuclear accumulation of beta-catenin. Nuclear beta-catenin is an establ...
Autores principales: | Vijmasi, Trinka, Prince, Eric, Hengartner, Astrid, Agwu, Chibueze, Staulcup, Susan, Pavlova, Maryna, Griesinger, Andrea, Donson, Andrew, Dorris, Kathleen, Handler, Michael, Hankinson, Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715255/ http://dx.doi.org/10.1093/neuonc/noaa222.719 |
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