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ATRT-13. DIFFERENT CELLS OF ORIGIN PAVE THE WAY FOR MOLECULAR HETEROGENEITY IN RHABDOID TUMORS
Rhabdoid tumors (RT) are rare but highly aggressive pediatric neoplasms. These tumors carry homozygous loss-of-function alterations of SMARCB1 in almost all cases with an otherwise low mutational load. RT arise at different intracranial (ATRT) as well as extracranial (MRT) anatomical sites. Three ma...
Autores principales: | Graf, Monika, Interlandi, Marta, Moreno, Natalia, Holdhof, Dörthe, Melcher, Viktoria, Kastrati, Dennis, zu Hörste, Gerd Meyer, Dugas, Martin, Frühwald, Michael C, Albert, Thomas K, Schüller, Ulrich, Kerl, Kornelius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715320/ http://dx.doi.org/10.1093/neuonc/noaa222.012 |
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