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LGG-14. MULTI-OMIC ANALYSIS OF MAPK ACTIVATION IN PEDIATRIC PILOCYTIC ASTROCYTOMA
Pilocytic astrocytomas (PA) are low-grade gliomas (pLGG) and are the most frequent childhood brain tumors. They are characterized by oncogene-induced senescence (OIS) initiated and sustained by senescence-associated secretory phenotype (SASP) factors. OIS and SASP in PA are thought to be driven by a...
Autores principales: | Sigaud, Romain, Selt, Florian, Hielscher, Thomas, Overbeck, Nina, Usta, Diren, Remke, Marc, Picard, Daniel, Pfister, Stephan M, Jones, David T W, Brummer, Tilman, Witt, Olaf, Milde, Till |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715327/ http://dx.doi.org/10.1093/neuonc/noaa222.396 |
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