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ATRT-08. A PHASE II STUDY OF CONTINUOUS LOW DOSE PANOBINOSTAT IN PAEDIATRIC PATIENTS WITH MALIGNANT RHABDOID TUMORS/ATYPICAL TERATOID RHABDOID TUMORS

BACKGROUND: Panobinostat treatment has been shown to terminally differentiate malignant rhabdoid tumor (MRT)/atypical teratoid rhabdoid tumors (ATRT) in pre-clinical models. This is an open label, phase II study of panobinostat in patients with newly diagnosed or relapsed MRT/ATRT. AIMS: To assess t...

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Detalles Bibliográficos
Autores principales: Wood, Paul, Desai, Jayesh, Waldeck, Kelly, Cain, Jason, Gottardo, Nick, Strong, Robyn, Kinross, Kathryn, Carr, Michelle, Jones, Janelle, Wong, Lily, Ziegler, David, Hansford, Jordan, Michael, Michael, Ashley, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715339/
http://dx.doi.org/10.1093/neuonc/noaa222.008