MBRS-13. MiR-1253 POTENTIATES CISPLATIN RESPONSE IN PEDIATRIC MEDULLOBLASTOMA BY REGULATING FERROPTOSIS

Despite improvements in targeted therapies, few group 3 medulloblastoma patients survive long-term. Haploinsufficiency of 17p13.3 is a hallmark of these high-risk tumors; included within this locus is miR-1253, which has tumor suppressive properties in medulloblastoma. Therapeutic strategies capital...

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Detalles Bibliográficos
Autores principales: Kanchan, Ranjana K, Perumal, Naveenkumar, Atri, Pranita, Venkata, Ramakanth Chirravuri, Thapa, Ishwor, Nasser, Mohd Wasim, Batra, Surinder K, Mahapatra, Sidharth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Medulloblastoma (Research)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715387/
http://dx.doi.org/10.1093/neuonc/noaa222.530

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