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TBIO-06. BDNF-TRKB SIGNALING REGULATES NEURON-GLIOMA SYNAPTOGENESIS AND PROMOTES TUMOR PROGRESSION

Pediatric high-grade gliomas (pHGG) are a devastating group of diseases that urgently require novel therapeutic options. We have previously demonstrated that pHGGs hijack mechanisms of brain development and plasticity to their advantage. Here, we investigated the role of microenvironmental BDNF on p...

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Detalles Bibliográficos
Autores principales:	Taylor, Kathryn, Zhang, Helena, Hui, Alexa, Gillespie, Shawn, Monje, Michelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Tumor Biology (not fitting a specific disease category)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715419/ http://dx.doi.org/10.1093/neuonc/noaa222.834

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