RARE-31. RECURRENT CHOROID PLEXUS CARCINOMA IN THE SETTING OF LI-FRAUMENI SYNDROME: REPORT OF TWO CHILDREN MANAGED WITH INTENSIVE RE-INDUCTION AND MARROW-ABLATIVE CONSOLIDATION CHEMOTHERAPY WITHOUT IRRADIATION FOLLOWED BY MOLECULARLY-TARGETED BIOLOGICAL THERAPY

BACKGROUND: The optimal management for children with recurrent choroid plexus carcinoma (CPC), is not established. We report two children with germline TP53 mutations, whose CPC relapses were managed with marrow-ablative chemotherapy and oral biologically-targeted therapies. PATIENTS: Patient A: A 1...

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Detalles Bibliográficos
Autores principales: Shatara, Margaret, Filipek, Iwona, Ciołkowski, Maciej, Kowalczyk, Paweł, Osorio, Diana S, AbdelBaki, Mohamed S, Varga, Elizabeth A, Abu-Arja, Rolla, Heinerich, Claire, Boué, Daniel R, Pierson, Christopher R, Jones, Jeremy, Cottrell, Catherine E, Mardis, Elaine R, Wilson, Richard K, Leonard, Jeffrey R, Finlay, Jonathan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Craniopharyngioma and Rare Tumors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715442/
http://dx.doi.org/10.1093/neuonc/noaa222.741

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