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MODL-13. GENETICALLY ENGINEERED PIG MODEL OF RHABDOID TUMOR PREDISPOSITION SYNDROME-1

Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of children below 6 months of age. The majority of AT/RT demonstrate genomic alterations in the SMARCB1 gene. There are two major hurdles in the development of safe and effective treatments for AT/RT: first, the mouse mo...

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Detalles Bibliográficos
Autores principales:	Na, Brian, Rubinstein, C Dustin, Meudt, Jennifer J, Biegel, Jaclyn A, Judkins, Alexander R, Lehman, Brent P, Reichert, Jamie L, Vitte, Jeremie, Shanmuganayagam, Dhanansayan, Giovannini, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715455/ http://dx.doi.org/10.1093/neuonc/noaa222.587

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