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OTHR-16. CONCURRENT USE OF APREPITANT AND IFOSFAMIDE IN PEDIATRIC CANCER PATIENTS

BACKGROUND: Aprepitant, a selective neurokinin-1 receptor antagonist, is commonly used for prevention of chemotherapy-induced nausea and vomiting. Its use with ifosfamide is controversial due to the putative risk of potentiating neurotoxicity via inhibition of cytochrome P450 3A4 (CYP3A4). The curre...

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Detalles Bibliográficos
Autores principales:	Winzent, Shelby, Dahl, Nathan, Hemenway, Molly, Lovria, Rachel, Dorris, Kathleen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Others (Not Fitting Any Other Category)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715537/ http://dx.doi.org/10.1093/neuonc/noaa222.637

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