Cargando…

THER-02. EVALUATION OF THE ONCOLYTIC VIRUS DELTA24-RGD AS AN ANTI-TUMOR AGENT IN PRECLINICAL MODELS OF LOCALIZED AND DISSEMINATED AT/RT

Current therapies for atypical teratoid/rhabdoid tumors (AT/RTs) are suboptimal, resulting in a 2-year OS below 20% and the development of severe side effects. Therefore, we need to explore alternative therapeutic approaches for this disease. Since the virus Delta24-RGD has already demonstrated its...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garcia-Moure, Marc, González-Huarriz, Marisol, de la Nava, Daniel, Marrodán, Lucía, Gomez-Manzano, Cande, Fueyo, Juan, Patiño-García, Ana, Alonso, Marta M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Viral/Gene Therapy and other Novel Therapies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715559/ http://dx.doi.org/10.1093/neuonc/noaa222.852

Ejemplares similares

THER-09. ONCOLYTIC ADENOVIRUS, DNX-2401, FOR NAIVE DIFFUSE INTRINSIC PONTINE GLIOMAS: A PHASE I CLINICAL TRIAL
por: Iñigo-Marco, Ignacio, et al.
Publicado: (2020)

THER-01. AWAKING THE IMMUNE SYSTEM WITH AN IMMUNO-ONCOLYTIC VIRUS AS A THERAPEUTIC STRATEGY FOR DIPGs
por: Laspidea, Virginia, et al.
Publicado: (2020)

THER-02. Pediatric brain tumor cultures reveal differential susceptibility to four oncolytic viruses
por: Vazaios, Konstantinos, et al.
Publicado: (2022)

THER-04. IS THERE A ROLE FOR CANNABIDIOL IN THE TREATMENT OF CHILDHOOD BRAIN TUMOURS?
por: Lockwood, George, et al.
Publicado: (2020)

THER-07. INHIBITION OF THE RAS SIGNALING ENHANCES VIRAL ONCOLYSIS IN MALIGNANT GLIOMAS
por: Arakawa, Yoshiki, et al.
Publicado: (2020)

THER-01. Precision brain tumor therapy by AAV-mediated oncogene editing
por: von Soosten, Laura, et al.
Publicado: (2022)

THER-03. IN VITRO EVALUATION OF THE EFFECT OF CANNABIDIOL ON PAEDIATRIC BRAIN TUMOUR CELL LINES USING A PULSED TREATMENT REGIME
por: Faulkes, Sophie, et al.
Publicado: (2020)

THER-05. GENETICALLY STABLE POLIOVIRUS VECTOR CARRYING H3.3K27M ANTIGEN FOR TREATMENT OF DIFFUSE MIDLINE GLIOMA BY INTRAMUSCULAR INJECTION
por: Mosaheb, Mubeen, et al.
Publicado: (2020)

THER-08. SGT53 – A NOVEL p53 NANOMEDICINE INDUCES SIGNIFICANT RESPONSES IN CHILDREN WITH RECURRENT MEDULLOBLASTOMA AND CHOROID PLEXUS CARCINOMA: A REPORT OF TWO CASES
por: Hwang, Eugene, et al.
Publicado: (2020)

THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIOMA AND INTRACEREBELLAR MEDULLOBLASTOMA
por: Richardson, Angela, et al.
Publicado: (2020)

Convection Enhanced Delivery of the Oncolytic Adenovirus Delta24-RGD in Patients with Recurrent GBM: A Phase I Clinical Trial Including Correlative Studies
por: van Putten, Erik H.P., et al.
Publicado: (2022)

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1
por: Carlisle, Robert C., et al.
Publicado: (2009)

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage
por: Binny, Christopher, et al.
Publicado: (2012)

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells
por: Zhang, Fang, et al.
Publicado: (2007)

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells
por: Flynn, Rowan, et al.
Publicado: (2015)

Prognostic impact of corticosteroids on efficacy of chimeric antigen receptor T-cell therapy in large B-cell lymphoma
por: Strati, Paolo, et al.
Publicado: (2021)

Pharmacokinetic analysis identifies a factor VIII immunogenicity threshold after AAV gene therapy in hemophilia A mice
por: Lundgren, Taran S., et al.
Publicado: (2022)

Comparative effectiveness of ZUMA-5 (axi-cel) vs SCHOLAR-5 external control in relapsed/refractory follicular lymphoma
por: Ghione, Paola, et al.
Publicado: (2022)

In vivo HSC transduction in rhesus macaques with an HDAd5/3+ vector targeting desmoglein 2 and transiently overexpressing cxcr4
por: Wang, Hongjie, et al.
Publicado: (2022)

Transcutaneous ultrasound-mediated gene delivery into canine livers achieves therapeutic levels of factor VIII expression
por: Manson, Megan A., et al.
Publicado: (2022)

CD14(+)/CD31(+) monocytes expanded by UM171 correct hemophilia A in zebrafish upon lentiviral gene transfer of factor VIII
por: Elnaggar, Muhammad, et al.
Publicado: (2022)

In vivo HSC prime editing rescues sickle cell disease in a mouse model
por: Li, Chang, et al.
Publicado: (2023)

Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells
por: Vavassori, Valentina, et al.
Publicado: (2023)

Adenine base editor–mediated correction of the common and severe IVS1-110 (G>A) β-thalassemia mutation
por: Hardouin, Giulia, et al.
Publicado: (2023)

Stable and durable factor IX levels in patients with hemophilia B over 3 years after etranacogene dezaparvovec gene therapy
por: von Drygalski, Annette, et al.
Publicado: (2022)

Identification of evolutionary mechanisms of myelomatous effusion by single-cell RNA sequencing
por: Sun, Zhengxu, et al.
Publicado: (2023)

A comprehensive landscape of transcription profiles and data resources for human leukemia
por: Luo, Mei, et al.
Publicado: (2023)

Intrathymic AAV delivery results in therapeutic site-specific integration at TCR loci in mice
por: Calabria, Andrea, et al.
Publicado: (2023)

CAR NK-92 cell–mediated depletion of residual TCR(+) cells for ultrapure allogeneic TCR-deleted CAR T-cell products
por: Kath, Jonas, et al.
Publicado: (2023)

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models
por: Martínez-Vélez, Naiara, et al.
Publicado: (2019)

The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models
por: Garcia-Moure, Marc, et al.
Publicado: (2019)

Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory
por: Martinez-Velez, Naiara, et al.
Publicado: (2022)

IMMU-01. THE ONCOLYTIC VIRUS DELTA-24-RGD IN COMBINATION WITH AN AGONISTIC CD40 MAB INDUCES A DURABLE AND SYNERGISTIC ANTI-TUMOR IMMUNE EFFECT IN DIPG PRECLINICAL MODELS
por: Labiano, Sara, et al.
Publicado: (2021)

DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report
por: Tejada, Sonia, et al.
Publicado: (2018)

Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis
por: Lacroix, Jeannine, et al.
Publicado: (2014)

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models
por: Martinez-Velez, Naiara, et al.
Publicado: (2019)

HGG-15. THE IMIPRIDONE ONC201 IN COMBINATION WITH THE ONCOLYTIC ADENOVIRUS DELTA-24-RGD HAS A SYNERGISTIC EFFECT IN PRECLINICAL MODELS OF PHGGS AND DMGS
por: de la Nava, Daniel, et al.
Publicado: (2021)

Triptans in clinical practice: the basic scientist’s point of view
por: Buzzi, M. Gabriella
Publicado: (2001)

Clinical experience with triptans
por: Zanchin, Giorgio, et al.
Publicado: (2001)

Triptans: the experience of a clinical pharmacologist in clinical practice
por: Pini, Luigi Alberto, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_dqm3bcu29qkeefc2ai8ggid3ch