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ATRT-18. SHH-SUBTYPE ATYPICAL TERATOID/RHABDOID TUMORS ARE SELECTIVELY SENSITIVE TO GEMCITABINE TREATMENT
Atypical Teratoid Rhabdoid Tumors (ATRT) are highly malignant embryonal tumors of the central nervous system with a dismal prognosis. ATRT can be divided into three molecular subgroups of which the Sonic Hedgehog (SHH) subgroup is most prevalent. In this study, we developed and validated a novel pat...
Autores principales: | Metselaar, Dennis, Meel, Michaël Hananja, Goulding, Joshua, Waranecki, Piotr, de Gooijer, Mark, Breur, Marjolein, van Zanten, Sophie Veldhuizen, Bugiani, Marianna, Wesseling, Pieter, Kaspers, Gertjan, Hulleman, Esther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715563/ http://dx.doi.org/10.1093/neuonc/noaa222.017 |
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