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RARE-52. RB1 GENE DELETIONS ARE THE NOVEL MECHANISM OF CHOROID PLEXUS TUMORS (CPT) ONCOGENESIS

BACKGROUND: CPTs are known to be rare TP53-dependent neoplasms, while major molecular alterations underlying tumor progression, especially in TP53-wild type cases, are still unclear. METHODS: 18 primary CPT, including 16 choroid plexus carcinomas (CPC) and two atypical choroid plexus papillomas (CPP...

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Detalles Bibliográficos
Autores principales: Druy, Alexander, Yasko, Liudmila, Valiakhmetova, Andge, Novichkova, Galina, Papusha, Liudmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715610/
http://dx.doi.org/10.1093/neuonc/noaa222.762