IMMU-13. DUAL IGF1R/IR INHIBITOR IN COMBINATION WITH GD2-CAR T-CELLS AS A POTENT THERAPEUTIC STRATEGY FOR H3K27M-MUTANT DIFFUSE MIDLINE GLIOMAS

Diffuse midline gliomas (DMG) are aggressive paediatric brain tumors for which there is no effective treatment. Recent pre-clinical studies suggest that adoptive transfer of chimeric antigen receptor (CAR) T-cells targeting the disialoganglioside antigen GD2 (GD2-CAR) has a significant therapeutic p...

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Detalles Bibliográficos
Autores principales: de Billy, Emmanuel, pellegrino, Marsha, De Angelis, Biagio, Businaro, Pietro, Orlando, Domenico, Pericoli, Giulia, Petrilli, Lucia Lisa, Rossi, Sabrina, Ferretti, Roberta, Maestro, Nicola, Massimi, Luca, Pezzullo, Marco, De Stefanis, Cristiano, Rota, Rossella, Ferrari, Francesco, Salviato, Elisa, Carai, Andrea, Caruana, Ignazio, Locatelli, Franco, Mastronuzzi, Angela, Quintarelli, Concetta, Vinci, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715675/
http://dx.doi.org/10.1093/neuonc/noaa222.369

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