Cargando…

SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?

OBJECTIVE: Our objective was to quantify resection outcomes and operative morbidity in paediatric brain tumour surgery using existing scales, assessing their applicability. METHODS: We investigated morbidity using the Clavien-Dindo (CD) scale and the Drake classification. All paediatric patients rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Foster, Mitchell, Hennigan, Dawn, Greystone, Rebecca, van Baarsen, Kirsten, Sunderland, Geraint, Millward, Christopher, Srinivasan, Harishchandra, Ferguson, Deborah, Totimeh, Teddy, Pizer, Barry, Mallucci, Conor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715701/
http://dx.doi.org/10.1093/neuonc/noaa222.808
_version_ 1783619016922759168
author Foster, Mitchell
Hennigan, Dawn
Greystone, Rebecca
van Baarsen, Kirsten
Sunderland, Geraint
Millward, Christopher
Srinivasan, Harishchandra
Ferguson, Deborah
Totimeh, Teddy
Pizer, Barry
Mallucci, Conor
author_facet Foster, Mitchell
Hennigan, Dawn
Greystone, Rebecca
van Baarsen, Kirsten
Sunderland, Geraint
Millward, Christopher
Srinivasan, Harishchandra
Ferguson, Deborah
Totimeh, Teddy
Pizer, Barry
Mallucci, Conor
author_sort Foster, Mitchell
collection PubMed
description OBJECTIVE: Our objective was to quantify resection outcomes and operative morbidity in paediatric brain tumour surgery using existing scales, assessing their applicability. METHODS: We investigated morbidity using the Clavien-Dindo (CD) scale and the Drake classification. All paediatric patients receiving a biopsy or craniotomy for an intracranial tumour in a single tertiary paediatric neurosurgery centre between January 2008 and December 2018 were studied. Complications up to day 30 post op were graded. RESULTS: There were 459 operations: 92 biopsies and 367 craniotomies comprising 166 infratentorial and 292 supratentorial tumours. Median age was 9 years (56% male). The surgical goal was achieved or exceeded in 94% of cases. Thirty-day mortality was 1.31% with all deaths related to disease and none to surgical complications. The overall CD score was 1 in 10.9% of cases, 2 in 18.9%, 3A in 1.7%, 3B in 11.8%, and 4 in 1.1%. There was no operative morbidity in 54% of cases. Using the Drake classification, meningitis was seen in 3.92% of cases, seizures in 3.92%, neurological deficit (that persisted at 30 days) in 8.5%, CSF leak in 5.01%, wound infection in 1.96%, haemorrhage 1.75 %, shunt infection in 1.53%, shunt block in 0.65%, medical complications in 2.4%, and others in 3.05%. CONCLUSIONS: This is the largest series presenting morbidity from paediatric brain tumour surgery, and the first to validate the CD scale. Our morbidity on the Drake scale was comparable with other series. There is a need to develop improved tools to quantify morbidity in this high-risk specialty.
format Online
Article
Text
id pubmed-7715701
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-77157012020-12-09 SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY? Foster, Mitchell Hennigan, Dawn Greystone, Rebecca van Baarsen, Kirsten Sunderland, Geraint Millward, Christopher Srinivasan, Harishchandra Ferguson, Deborah Totimeh, Teddy Pizer, Barry Mallucci, Conor Neuro Oncol Neurosurgery OBJECTIVE: Our objective was to quantify resection outcomes and operative morbidity in paediatric brain tumour surgery using existing scales, assessing their applicability. METHODS: We investigated morbidity using the Clavien-Dindo (CD) scale and the Drake classification. All paediatric patients receiving a biopsy or craniotomy for an intracranial tumour in a single tertiary paediatric neurosurgery centre between January 2008 and December 2018 were studied. Complications up to day 30 post op were graded. RESULTS: There were 459 operations: 92 biopsies and 367 craniotomies comprising 166 infratentorial and 292 supratentorial tumours. Median age was 9 years (56% male). The surgical goal was achieved or exceeded in 94% of cases. Thirty-day mortality was 1.31% with all deaths related to disease and none to surgical complications. The overall CD score was 1 in 10.9% of cases, 2 in 18.9%, 3A in 1.7%, 3B in 11.8%, and 4 in 1.1%. There was no operative morbidity in 54% of cases. Using the Drake classification, meningitis was seen in 3.92% of cases, seizures in 3.92%, neurological deficit (that persisted at 30 days) in 8.5%, CSF leak in 5.01%, wound infection in 1.96%, haemorrhage 1.75 %, shunt infection in 1.53%, shunt block in 0.65%, medical complications in 2.4%, and others in 3.05%. CONCLUSIONS: This is the largest series presenting morbidity from paediatric brain tumour surgery, and the first to validate the CD scale. Our morbidity on the Drake scale was comparable with other series. There is a need to develop improved tools to quantify morbidity in this high-risk specialty. Oxford University Press 2020-12-04 /pmc/articles/PMC7715701/ http://dx.doi.org/10.1093/neuonc/noaa222.808 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Neurosurgery
Foster, Mitchell
Hennigan, Dawn
Greystone, Rebecca
van Baarsen, Kirsten
Sunderland, Geraint
Millward, Christopher
Srinivasan, Harishchandra
Ferguson, Deborah
Totimeh, Teddy
Pizer, Barry
Mallucci, Conor
SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?
title SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?
title_full SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?
title_fullStr SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?
title_full_unstemmed SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?
title_short SURG-12. PAEDIATRIC BRAIN TUMOUR SURGERY: HOW CAN WE REPORT OUR SURGICAL OUTCOMES AND OPERATIVE MORBIDITY?
title_sort surg-12. paediatric brain tumour surgery: how can we report our surgical outcomes and operative morbidity?
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715701/
http://dx.doi.org/10.1093/neuonc/noaa222.808
work_keys_str_mv AT fostermitchell surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT hennigandawn surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT greystonerebecca surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT vanbaarsenkirsten surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT sunderlandgeraint surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT millwardchristopher surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT srinivasanharishchandra surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT fergusondeborah surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT totimehteddy surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT pizerbarry surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity
AT mallucciconor surg12paediatricbraintumoursurgeryhowcanwereportoursurgicaloutcomesandoperativemorbidity