EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ

Ependymoma represents a heterogeneous disease affecting the entire neuraxis. Extensive molecular profiling efforts have identified molecular ependymoma subgroups based on DNA methylation. However, the intratumoral heterogeneity and developmental origins of these groups are only partially understood,...

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Autores principales: Englinger, Bernhard, Gojo, Johannes, Jiang, Li, Hübner, Jens M, Shaw, McKenzie L, Hack, Olivia A, Madlener, Sibylle, Kirchhofer, Dominik, Liu, Ilon, Pyrdol, Jason, Hovestadt, Volker, Mazzola, Emanuele, Mathewson, Nathan D, Trissal, Maria, Lötsch, Daniela, Berger, Walter, Dorfer, Christian, Haberler, Christine, Halfmann, Angela, Mayr, Lisa, Peyrl, Andreas, Geyeregger, Rene, Pajtler, Kristian W, Milde, Till, Geduldig, Jack E, Pelton, Kristine, Czech, Thomas, Ashenberg, Orr, Wucherpfennig, Kai W, Rozenblatt-Rosen, Orit, Alexandrescu, Sanda, Ligon, Keith L, Pfister, Stefan M, Regev, Aviv, Slavc, Irene, Suva, Mario L, Kool, Marcel, Filbin, Mariella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Ependymoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715721/
http://dx.doi.org/10.1093/neuonc/noaa222.158

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