MBRS-53. CONTROL OF MEDULLOBLASTOMA VASCULATURE BY A REGULATOR OF NEUROGENESIS

Medulloblastomas are characterized by poor neuronal lineage specification. Expression of the RE1 Silencing Transcription Factor (REST), a regulator of neurogenesis, is aberrantly elevated in human sonic hedgehog (SHH) medulloblastomas. Using a novel transgenic mouse (REST(TG)) model, we demonstrated...

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Detalles Bibliográficos
Autores principales: Shaik, Shavali, Maegawa, Shinji, Haltom, Amanda, Dobson, Tara, Schadler, Keri, Gopalakrishnan, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Medulloblastoma (Research)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715809/
http://dx.doi.org/10.1093/neuonc/noaa222.559

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