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LGG-30. TRAMETINIB-ASSOCIATED HYPONATREMIA IN A CHILD WITH LOW GRADE GLIOMA IS NOT SEEN FOLLOWING TREATMENT WITH ALTERNATIVE MEK INHIBITOR

Molecularly targeted therapy with MEK inhibitors is increasingly being incorporated into the treatment of pediatric low-grade gliomas (LGGs). Trametinib is an orally available MEK1/2 inhibitor that has demonstrated tumor control in LGGs with BRAF alterations. Safe expansion of MEK inhibitor therapy...

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Detalles Bibliográficos
Autores principales:	Lazow, Margot A, Lawson, Sarah A, Salloum, Ralph, Hummel, Trent R, Smiley, Natasha Pillay, DeWire-Schottmiller, Mariko D, Fouladi, Maryam, de Blank, Peter M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Low Grade Glioma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715810/ http://dx.doi.org/10.1093/neuonc/noaa222.412

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