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IMMU-22. PHASE IB IMMUNOTHERAPY CLINICAL TRIAL WITH THE USE OF AUTOLOGOUS DENDRITIC CELLS PULSED WITH AN ALLOGENIC TUMORAL CELL LINES LYSATE IN PATIENTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a lethal condition, and therefore novel approaches are needed. Monocyte-derived dendritic cells (mDCs) pulsed with tumor antigens, as professional antigen-presenting cells, are a promising strategy for immunotherapy of invasive brain tumors. MET...
Autores principales: | Madrid, Andres Morales La, Mora, Jaume, Cruz, Ofelia, Lopez, Vicente Santa-Maria, Perez-Jaume, Sara, Guillen, Antonio, Paco, Sonia, Carcaboso, Angel M, Puerta, Patricia, Salvador, Noelia, Juan, Manuel, Benitez-Ribas, Daniel, Cabezon, Raquel, Flórez-Grau, Georgina, Molero, Mari Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715823/ http://dx.doi.org/10.1093/neuonc/noaa222.378 |
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