MBRS-01. DISSECTING REGULATORS OF THE ABERRANT POST-TRANSCRIPTIONAL LANDSCAPE IN MYC-AMPLIFIED GROUP 3 MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common solid malignant pediatric brain neoplasm, with Group 3 (G3) MB representing the most aggressive subgroup. MYC amplification is an independent poor prognostic factor in G3 MB, however, therapeutic targeting of the MYC pathway remains limited and alternative the...

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Detalles Bibliográficos
Autores principales: Kameda-Smith, Michelle, Zhu, Helen, Luo, EnChing, Venugopal, Chitra, Xella, Agata, Brown, Kevin, Fox, Raymond, Yee, Brian, Xing, Sansi, Tan, Frederick, Bakhshinyan, David, Adile, Ashley, Subapanditha, Minomi, Picard, Daniel, Moffat, Jason, Fleming, Adam, Hope, Kristin, John, Provias, Remke, Marc, Lu, Yu, Reya, Tannishitha, Reimand, Juri, Wechsler-Reya, Robert, Yeo, Gene, Singh, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Medulloblastoma (Research)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715904/
http://dx.doi.org/10.1093/neuonc/noaa222.522

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