Cargando…

ATRT-25. INTEGRATED QUANTITATIVE SWATH-MS PROTEOMICS ANALYSIS OF ATRTs UNCOVERS NEW THERAPEUTIC OPPORTUNITIES

The consequences of SMARCB1 loss in Atypical Teratoid Rhabdoid Tumors (ATRTs) have been extensively characterized at the epigenetic/transcriptomic level. In this study we detail the functional effect of SMARCB1 mutation on the MRT proteome, its relationship with RNA deregulation or lack thereof. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Finetti, Martina Anna, Hacking, James, Lishman-Walker, Emma, Synowsky, Silvia A, Crosier, Stephen, Martin, Emmma, Burns, Jess, Shirran, Sally L, Bailey, Simon, Clifford, Steven C, Huang, Paul, Williamson, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Atypical Teratoid/Rhabdoid Tumors
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715928/ http://dx.doi.org/10.1093/neuonc/noaa222.024

Ejemplares similares

ATRT-33. ENABLING RAPID CLASSIFICATION OF ATRT WITH NANOSTRING NCOUNTER PLATFORM
por: Ho, Ben, et al.
Publicado: (2020)

ATRT-27. COST-EFFECTIVE ASSAYS TO SUBGROUP ATRT IN THE DAILY ROUTINE
por: Lobon-Iglesias, María-Jesús, et al.
Publicado: (2020)

ATRT-24. CELL SURFACE PROTEOME ANALYSIS OF ATRT IDENTIFIES TARGETS FOR IMMUNOTHERAPY
por: Cole, Allison, et al.
Publicado: (2020)

ATRT-14. MACROPHAGE-TUMOR CELL INTERACTION PROMOTES ATRT PROGRESSION AND CHEMORESISTANCE
por: Melcher, Viktoria, et al.
Publicado: (2020)

ATRT-28. SINGLE NUCLEI SEQUENCING REVEALS THE DIFFERENT PHENOTYPIC COMPOSITION OF THE ATRT SUBGROUPS
por: Johann, Pascal, et al.
Publicado: (2020)

ATRT-08. TARGETING THE TP53-MDM2 ENHANCES RADIATION SENSITIVITY IN ATRT
por: Alimova, Irina, et al.
Publicado: (2021)

ATRT-05. REPURPOSED ANTI-MALARIAL QUINACRINE ACTIVATES P53 AND INHIBITS ATRT TUMORIGENICITY
por: Kaur, Harpreet, et al.
Publicado: (2021)

ATRT-31. SUCCESSFUL MULTIMODALITY MANAGEMENT OF ATRT OF THE LOWER DORSAL SPINE WITH SPINAL DROP METASTASIS
por: Biswas, Ahitagni, et al.
Publicado: (2020)

ATRT-15. LY6D – A CANDIDATE FOR NANOPARTICLE-BASED TARGETED THERAPIES OF ATRT
por: Hagemeier, Lea, et al.
Publicado: (2020)

ATRT-23. SIRT2 cooperates with SMARCB1 to induce a differentiation block in ATRT
por: Alimova, Irina, et al.
Publicado: (2022)

ATRT-16. MODELLING ATRT THROUGH SWI/SNF COMPLEX DEFICIENCY IN GENETICALLY-ENGINEERED MOUSE MODELS
por: Bondoc, Andrew, et al.
Publicado: (2020)

ATRT-13. An integrative analysis of the ATRT proteome unravels novel drug targets and refines molecular subgrouping
por: Johann, Pascal, et al.
Publicado: (2022)

ATRT-19. Functional genomics reveal distinct modulators of response to CDK4/6 inhibitors in ATRTs
por: Merk, Daniel, et al.
Publicado: (2022)

ATRT-10. Single-cell transcriptional profiling of ATRTs reveals heterogeneous signatures of tumor and non-malignant cell populations
por: Blanco-Carmona, Enrique, et al.
Publicado: (2022)

ATRT-20. CDK7 INHIBITION IN AT/RT
por: Morin, Andrew, et al.
Publicado: (2020)

ATRT-24. CDK7 Inhibition in AT/RT
por: Morin, Andrew, et al.
Publicado: (2022)

ATRT-05. RESULTS OF MULTICENTER TRIAL CONCERNING THE TREATMENT OF CHILDREN WITH ATYPICAL TERATOID/RHABDOID TUMORS (ATRT) OF THE CENTRAL NERVOUS SYSTEM
por: Zheludkova, Olga, et al.
Publicado: (2020)

ATRT-07. HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS STEM CELL TRANSPLANTATION FOR AN ADULT PRESENTATION OF THE ATYPICAL TERATOID-RHABDOID TUMOR (ATRT)
por: Mrugala, Maciej, et al.
Publicado: (2020)

ATRT-06. Atypical Teratoid Rhabdoid Tumors (ATRT): results from a Single Institution in Brazil - São Paulo University
por: Barreto, Juliana Silveira, et al.
Publicado: (2022)

ATRT-11. Anatomico-biological correlations define a new layer for ATRT molecular subgroups pointing to potential lineages of origin
por: Lobon-Iglesias, Maria, et al.
Publicado: (2022)

ATRT-05. Infants and newborns with atypical teratoid/rhabdoid tumors (ATRT) and extracranial malignant rhabdoid tumors: a unique and challenging population
por: Nemes, Karolina, et al.
Publicado: (2022)

ATRT-32. GENOME-WIDE CRISPR AND SMALL-MOLECULE SCREENS UNCOVER TARGETABLE DEPENDENCIES IN AT/RTs
por: Merk, Daniel, et al.
Publicado: (2020)

ATRT-06. SMARCB1 LOSS DRIVEN NON-CANONICAL PRC1 ACTIVITY REGULATES DIFFERENTIATION IN ATYPICAL TERATOID RHABDOID TUMORS (ATRT)
por: Alimova, Irina, et al.
Publicado: (2020)

ATRT-09. IDENTIFICATION OF POTENTIAL GENETIC DRIVERS OF METHOTREXATE (MTX) RESISTANCE IN ATYPICAL TERATOID RHABDOID TUMOURS (ATRT) THROUGH A GENOME-WIDE RNAI SCREEN
por: Kannappan, Sunand, et al.
Publicado: (2021)

ATRT-07. Low-grade diffusely infiltrative tumor, SMARCB1-mutant: a clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC
por: Thomas, Christian, et al.
Publicado: (2022)

ATRT-01. Reconstitution of cGAS/ STING pathway via epigenetic reprogramming leads to anti-viral inflammatory signaling in Atypical teratoid rhabdoid tumors (ATRTs)
por: Mangoli, Avani, et al.
Publicado: (2022)

ATRT-19. EPIGENETIC REPROGRAMMING LEADS TO INNATE IMMUNE PATHWAY ACTIVATION IN AT/RT
por: Hariharan, Seethalakshmi, et al.
Publicado: (2020)

ATRT-02. MEK/ERK SIGNALLING DEPENDENCY IN ATYPICAL TERATOID RHABDOID TUMOURS
por: Shi, Hui (Claire), et al.
Publicado: (2020)

ATRT-17. TARGETING GLUTAMINE METABOLISM LOWERS METHYLATION POTENCIALS IN AT/RT AND SYNERGIZE WITH TAZEMETOSTAT
por: Nakata, Satoshi, et al.
Publicado: (2020)

ATRT-10. ATYPICAL TERATOID/RHABDOID TUMOR OF THE PINEAL REGION IN A PEDIATRIC PATIENT
por: Almeida, Carlos, et al.
Publicado: (2020)

ATRT-13. DIFFERENT CELLS OF ORIGIN PAVE THE WAY FOR MOLECULAR HETEROGENEITY IN RHABDOID TUMORS
por: Graf, Monika, et al.
Publicado: (2020)

ATRT-18. Atypical Teratoid/Rhabdoid Tumor in Children: Case Reports from Indonesia
por: Ramadhan, Diko Anugrah, et al.
Publicado: (2022)

ATRT-09. IDENTIFICATION OF HUB GENES IN ATYPICAL TERATOID/RHABDOID TUMORS BY MULTIPLE-MICROARRAY ANALYSIS
por: Liu, Wei, et al.
Publicado: (2020)

ATRT-18. SHH-SUBTYPE ATYPICAL TERATOID/RHABDOID TUMORS ARE SELECTIVELY SENSITIVE TO GEMCITABINE TREATMENT
por: Metselaar, Dennis, et al.
Publicado: (2020)

ATRT-07. DEFINING LOST AND GAINED TRANSCRIPTIONAL REGULATORY NETWORKS IN ATYPICAL TERATOID RHABDOID TUMOR
por: Nesvick, Cody, et al.
Publicado: (2021)

ATRT-26. META-ANALYSIS OF TREATMENT MODALITIES IN METASTATIC ATYPICAL TERATOID/RHABDOID TUMORS IN CHILDREN
por: Underiner, Reena M, et al.
Publicado: (2020)

ATRT-21. Contribution of germline mosaic alterations of SMARCB1 in rhabdoid tumor predisposition syndrome
por: Masliah-Planchon, Julien, et al.
Publicado: (2022)

ATRT-12. LIN28A expression correlates with poor prognosis and the MYC subgroup in AT/RTs
por: Dottermusch, Matthias, et al.
Publicado: (2022)

ATRT-30. RETROSPECTIVE ANALYSIS OF CHILDREN WITH ATYPICAL TERATOID RHABDOID TUMOR TREATED ACCORDING TO ACNS0333
por: Hoffman, Lindsey, et al.
Publicado: (2020)

ATRT-01. IDENTIFICATION OF MICRORNA-BASED PROGNOSTIC BIOMARKERS AND CANDIDATE THERAPEUTIC AGENTS FOR ATYPICAL TERATOID/RHABDOID TUMOR
por: Zhang, Yang
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jpjvrbulfgav18fuf8cv68g2s2