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Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations

Agranulocytosis is a rare yet severe idiosyncratic adverse drug reaction to metamizole, an analgesic widely used in countries such as Switzerland and Germany. Notably, an underlying mechanism has not yet been fully elucidated and no predictive factors are known to identify at-risk patients. With the...

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Detalles Bibliográficos
Autores principales: Cismaru, Anca Liliana, Rudin, Deborah, Ibañez, Luisa, Liakoni, Evangelia, Bonadies, Nicolas, Kreutz, Reinhold, Carvajal, Alfonso, Lucena, Maria Isabel, Martin, Javier, Sancho Ponce, Esther, Molokhia, Mariam, Eriksson, Niclas, Krähenbühl, Stephan, Largiadèr, Carlo R., Haschke, Manuel, Hallberg, Pär, Wadelius, Mia, Amstutz, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716224/
https://www.ncbi.nlm.nih.gov/pubmed/33138277
http://dx.doi.org/10.3390/genes11111275