Cargando…

Interindividual Differences in Human Intestinal Microbial Conversion of (−)-Epicatechin to Bioactive Phenolic Compounds

[Image: see text] To quantify interindividual differences in the human intestinal microbial metabolism of (−)-epicatechin (EC), in vitro anaerobic incubations with fecal inocula from 24 healthy donors were conducted. EC-derived colonic microbial metabolites were qualitatively and quantitively analyz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chen, Vervoort, Jacques, Beekmann, Karsten, Baccaro, Marta, Kamelia, Lenny, Wesseling, Sebas, Rietjens, Ivonne M. C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716348/ https://www.ncbi.nlm.nih.gov/pubmed/33216536 http://dx.doi.org/10.1021/acs.jafc.0c05890

Ejemplares similares

Interindividual Differences in Human In Vitro Intestinal Microbial Conversion of Green Tea (‐)‐Epigallocatechin‐3‐O‐Gallate and Consequences for Activation of Nrf2 Mediated Gene Expression
por: Liu, Chen, et al.
Publicado: (2020)

Interindividual Differences in In Vitro Human Intestinal Microbial Conversion of 3-Acetyl-DON and 15-Acetyl-DON
por: Li, Fangfang, et al.
Publicado: (2022)

An in vitromodel to quantify interspecies differences in kinetics for intestinal microbial bioactivation and detoxification of zearalenone
por: Mendez-Catala, Diana M., et al.
Publicado: (2020)

Intra- and Inter-individual Differences in the Human Intestinal Microbial Conversion of (-)-Epicatechin and Bioactivity of Its Major Colonic Metabolite 5-(3′,4′-Dihydroxy-Phenyl)-γ-Valerolactone in Regulating Nrf2-Mediated Gene Expression
por: Liu, Chen, et al.
Publicado: (2022)

Effects of Maerua subcordata (Gilg) DeWolf on electrophile-responsive element (EpRE)-mediated gene expression in vitro
por: Gebrelibanos Hiben, Mebrahtom, et al.
Publicado: (2019)

Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Red Blood Cell Acetylcholinesterase Inhibition Following Exposure to Chlorpyrifos in the Caucasian and Chinese Population
por: Zhao, Shensheng, et al.
Publicado: (2019)

Use of Physiologically Based Kinetic Modeling to Predict Rat Gut Microbial Metabolism of the Isoflavone Daidzein to S‐Equol and Its Consequences for ERα Activation
por: Wang, Qianrui, et al.
Publicado: (2020)

Physiologically based kinetic modeling of the bioactivation of myristicin
por: Al-Malahmeh, Amer J., et al.
Publicado: (2016)

The potential health effects of dietary phytoestrogens
por: Rietjens, Ivonne M C M, et al.
Publicado: (2016)

Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice
por: Hoek-van den Hil, Elise F., et al.
Publicado: (2015)

Predicting the in vivo developmental toxicity of benzo[a]pyrene (BaP) in rats by an in vitro–in silico approach
por: Wang, Danlei, et al.
Publicado: (2021)

Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in basil-containing sauce of pesto
por: Al-Malahmeh, Amer J., et al.
Publicado: (2016)

Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf
por: Hiben, Mebrahtom Gebrelibanos, et al.
Publicado: (2020)

Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling
por: Ning, Jia, et al.
Publicado: (2017)

Use of Physiologically Based Pharmacokinetic Modeling to Predict Human Gut Microbial Conversion of Daidzein to S-Equol
por: Wang, Qianrui, et al.
Publicado: (2021)

Exploring Human Milk Dynamics: Interindividual Variation in Milk Proteome, Peptidome, and Metabolome
por: Dekker, Pieter M., et al.
Publicado: (2022)

Cellular levels and molecular dynamics simulations of estragole DNA adducts point at inefficient repair resulting from limited distortion of the double-stranded DNA helix
por: Yang, Shuo, et al.
Publicado: (2020)

Interindividual Variability in Biomarkers of Cardiometabolic Health after Consumption of Major Plant-Food Bioactive Compounds and the Determinants Involved
por: Milenkovic, Dragan, et al.
Publicado: (2017)

Differences in gut microbial fructoselysine degradation activity between breast-fed and formula-fed infants
por: van Dongen, Katja C W, et al.
Publicado: (2022)

Epicatechin elicits MyoD-dependent myoblast differentiation and myogenic conversion of fibroblasts
por: Lee, Sang-Jin, et al.
Publicado: (2017)

The role of metabolism in the developmental toxicity of polycyclic aromatic hydrocarbon‐containing extracts of petroleum substances
por: Kamelia, Lenny, et al.
Publicado: (2019)

Combining In Vitro Data and Physiologically Based Kinetic Modeling Facilitates Reverse Dosimetry to Define In Vivo Dose–Response Curves for Bixin‐ and Crocetin‐Induced Activation of PPARγ in Humans
por: Suparmi, Suparmi, et al.
Publicado: (2020)

Inter- and Intraindividual Differences in the Capacity of the Human Intestinal Microbiome in Fecal Slurries to Metabolize Fructoselysine and Carboxymethyllysine
por: van Dongen, Katja C. W., et al.
Publicado: (2022)

Phenolic Compounds and Bioactivity of Cytisus villosus Pourr.
por: Bouziane, Amel, et al.
Publicado: (2018)

Bioactivities of Phenolic Compounds from Kiwifruit and Persimmon
por: Kim, Young-Mo, et al.
Publicado: (2021)

Bioactive Phenolic Compounds from Peperomia obtusifolia
por: Ware, Ismail, et al.
Publicado: (2022)

Regulation of Cytochrome c Oxidase by Natural Compounds Resveratrol, (–)-Epicatechin, and Betaine
por: Lee, Icksoo
Publicado: (2021)

The Bioactive Potential of Functional Products and Bioavailability of Phenolic Compounds
por: Dabulici, Cristina Monica, et al.
Publicado: (2020)

The Role of Bioactive Phenolic Compounds on the Impact of Beer on Health
por: Ambra, Roberto, et al.
Publicado: (2021)

Evaluation of some in vitro bioactivities of sunflower phenolic compounds
por: Alexandrino, Thaís Dolfini, et al.
Publicado: (2021)

The Role of Endocrine and Dioxin-Like Activity of Extracts of Petroleum Substances in Developmental Toxicity as Detected in a Panel of CALUX Reporter Gene Assays
por: Kamelia, Lenny, et al.
Publicado: (2018)

Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach
por: Suparmi, Suparmi, et al.
Publicado: (2020)

Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent
por: Widjaja, Frances, et al.
Publicado: (2021)

A Systematic Review of the Efficacy of Bioactive Compounds in Cardiovascular Disease: Phenolic Compounds
por: Rangel-Huerta, Oscar D., et al.
Publicado: (2015)

GutSelf: Interindividual Variability in the Processing of Dietary Compounds by the Human Gastrointestinal Tract
por: Walther, Barbara, et al.
Publicado: (2019)

Assessment of Bioactive Phenolic Compounds and Antioxidant Activity of Blackberry Wines
por: Amidžić Klarić, Daniela, et al.
Publicado: (2020)

Next generation risk assessment of human exposure to estrogens using safe comparator compound values based on in vitro bioactivity assays
por: van Tongeren, Tessa C. A., et al.
Publicado: (2023)

Identification of epicatechin as the bioactive constituent in polyphenol enriched extracts that demonstrate a beneficial effect on allergic symptoms
por: Singh, A, et al.
Publicado: (2013)

Occurrence and Probabilistic Risk Assessment of Fumonisin B1, Fumonisin B2 and Deoxynivalenol in Nixtamalized Maize in Mexico City
por: Gilbert-Sandoval, Ixchel, et al.
Publicado: (2020)

Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro–In Silico Testing Strategy
por: Gilbert‐Sandoval, Ixchel, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cehgpnhjq5tmoqaj0avtnviagg