Targeting CD47/TNFAIP8 by miR-155 overcomes drug resistance and inhibits tumor growth through induction of phagocytosis and apoptosis in multiple myeloma

The mechanisms of drug resistance in multiple myeloma (MM) are poorly understood. Here we show that CD47, an integrin-associated receptor, is significantly up-regulated in drug resistant myeloma cells in comparison with parental cells, and that high expression of CD47 detected by immunohistochemistr...

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Detalles Bibliográficos
Autores principales: Rastgoo, Nasrin, Wu, Jian, Liu, Aijun, Pourabdollah, Maryam, Atenafu, Eshetu G., Reece, Donna, Chen, Wenming, Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716364/
https://www.ncbi.nlm.nih.gov/pubmed/33256380
http://dx.doi.org/10.3324/haematol.2019.227579

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