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Hematopoietic stem and progenitor cells use podosomes to transcellularly cross the bone marrow endothelium
Bone marrow endothelium plays an important role in the homing of hematopoietic stem and progenitor cells (HSPC) upon transplantation, but surprisingly little is known on how the bone marrow (BM) endothelial cells regulate local permeability and hematopoietic stem and progenitor cells transmigration....
Autores principales: | Rademakers, Timo, Goedhart, Marieke, Hoogenboezem, Mark, Ponce, Alexander García, van Rijssel, Jos, Samus, Maryna, Schnoor, Michael, Butz, Stefan, Huveneers, Stephan, Vestweber, Dietmar, Nolte, Martijn A., Voermans, Carlijn, van Buul, Jaap D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716366/ https://www.ncbi.nlm.nih.gov/pubmed/33256374 http://dx.doi.org/10.3324/haematol.2018.196329 |
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