Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity

The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and...

Descripción completa

Detalles Bibliográficos
Autor principal: Zarnescu, Daniela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716381/
https://www.ncbi.nlm.nih.gov/pubmed/33216116
http://dx.doi.org/10.1083/jcb.202010172
_version_ 1783619148372246528
author Zarnescu, Daniela C.
author_facet Zarnescu, Daniela C.
author_sort Zarnescu, Daniela C.
collection PubMed
description The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.
format Online
Article
Text
id pubmed-7716381
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-77163812021-06-07 Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity Zarnescu, Daniela C. J Cell Biol Spotlight The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity. Rockefeller University Press 2020-11-20 /pmc/articles/PMC7716381/ /pubmed/33216116 http://dx.doi.org/10.1083/jcb.202010172 Text en © 2020 Zarnescu https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Zarnescu, Daniela C.
Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity
title Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity
title_full Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity
title_fullStr Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity
title_full_unstemmed Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity
title_short Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity
title_sort think globally, act locally: centrosome-localized mrnas ensure mitotic fidelity
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716381/
https://www.ncbi.nlm.nih.gov/pubmed/33216116
http://dx.doi.org/10.1083/jcb.202010172
work_keys_str_mv AT zarnescudanielac thinkgloballyactlocallycentrosomelocalizedmrnasensuremitoticfidelity

Ejemplares similares