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Nanoparticle technology and its implications in endodontics: a review

BACKGROUND: The era of Nanomaterials has had a long lasting impression in the field of medical science. It’s excellent use in medicine has led to its application in dental science. Serious concerns regarding the eradication of microbial biofilms from the root canal system still exists in the field o...

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Autores principales: Raura, Natasha, Garg, Anirudh, Arora, Arpit, Roma, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716480/
https://www.ncbi.nlm.nih.gov/pubmed/33292702
http://dx.doi.org/10.1186/s40824-020-00198-z
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author Raura, Natasha
Garg, Anirudh
Arora, Arpit
Roma, M.
author_facet Raura, Natasha
Garg, Anirudh
Arora, Arpit
Roma, M.
author_sort Raura, Natasha
collection PubMed
description BACKGROUND: The era of Nanomaterials has had a long lasting impression in the field of medical science. It’s excellent use in medicine has led to its application in dental science. Serious concerns regarding the eradication of microbial biofilms from the root canal system still exists in the field of endodontics. Nanoparticles have proven to be much more efficient with good bonding capabilities and surface chemistry as compared to the conventional materials. The practical applications of nanotechnology in endodontics has led to future prospects in research in this field. MAIN BODY: Nanoparticles in endodontics have shown promising results. The various nanoaprticles like graphene, silver nanoparticles, chitosan, hydroxyapaptite nanoparticles, Iron compound, zirconia, Poly (lactic) co-glycolic acid, bioactive glass, mesoporous calcium silicate, titanium dioxide nanoparticles, Magnesium, Calcium oxide and Copper oxide have been discussed. These nanoparticles have fetched and shown great results in various application in endodontics like incorporation of nanoparticles in selaers, obturating materials, irrigation, and intracanal medicament. CONCLUSION: The application of nanoparticles from natural and synthetic materials is rapidly evolving in dentistry. These biomaterials have helped in treatment of oral diseases, in eradication of smear layer and biofilms, have been incorporated in various dental materials for their antimicrobial effects. Combining all their beneficial aspects, these nanoparticles will provide new paradigm shift in dentistry. This review on nanoparticles will provide the reader with the latest knowledge of these materials, their mechanism of action and its implications in endodontics.
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spelling pubmed-77164802020-12-04 Nanoparticle technology and its implications in endodontics: a review Raura, Natasha Garg, Anirudh Arora, Arpit Roma, M. Biomater Res Review BACKGROUND: The era of Nanomaterials has had a long lasting impression in the field of medical science. It’s excellent use in medicine has led to its application in dental science. Serious concerns regarding the eradication of microbial biofilms from the root canal system still exists in the field of endodontics. Nanoparticles have proven to be much more efficient with good bonding capabilities and surface chemistry as compared to the conventional materials. The practical applications of nanotechnology in endodontics has led to future prospects in research in this field. MAIN BODY: Nanoparticles in endodontics have shown promising results. The various nanoaprticles like graphene, silver nanoparticles, chitosan, hydroxyapaptite nanoparticles, Iron compound, zirconia, Poly (lactic) co-glycolic acid, bioactive glass, mesoporous calcium silicate, titanium dioxide nanoparticles, Magnesium, Calcium oxide and Copper oxide have been discussed. These nanoparticles have fetched and shown great results in various application in endodontics like incorporation of nanoparticles in selaers, obturating materials, irrigation, and intracanal medicament. CONCLUSION: The application of nanoparticles from natural and synthetic materials is rapidly evolving in dentistry. These biomaterials have helped in treatment of oral diseases, in eradication of smear layer and biofilms, have been incorporated in various dental materials for their antimicrobial effects. Combining all their beneficial aspects, these nanoparticles will provide new paradigm shift in dentistry. This review on nanoparticles will provide the reader with the latest knowledge of these materials, their mechanism of action and its implications in endodontics. BioMed Central 2020-12-04 /pmc/articles/PMC7716480/ /pubmed/33292702 http://dx.doi.org/10.1186/s40824-020-00198-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Raura, Natasha
Garg, Anirudh
Arora, Arpit
Roma, M.
Nanoparticle technology and its implications in endodontics: a review
title Nanoparticle technology and its implications in endodontics: a review
title_full Nanoparticle technology and its implications in endodontics: a review
title_fullStr Nanoparticle technology and its implications in endodontics: a review
title_full_unstemmed Nanoparticle technology and its implications in endodontics: a review
title_short Nanoparticle technology and its implications in endodontics: a review
title_sort nanoparticle technology and its implications in endodontics: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716480/
https://www.ncbi.nlm.nih.gov/pubmed/33292702
http://dx.doi.org/10.1186/s40824-020-00198-z
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