Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility

BACKGROUND: The efficacy of mesenchymal stromal cell (MSC) therapy is thought to depend on the intrinsic heterogeneity of MSC cultures isolated from different tissue sources as well as individual MSCs isolated from the same tissue source, neither of which is well understood. To study this, we used M...

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Detalles Bibliográficos
Autores principales: Harman, Rebecca M., Patel, Roosheel S., Fan, Jennifer C., Park, Jee E., Rosenberg, Brad R., Van de Walle, Gerlinde R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716481/
https://www.ncbi.nlm.nih.gov/pubmed/33276815
http://dx.doi.org/10.1186/s13287-020-02043-5

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