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CSE/H(2)S system alleviates uremic accelerated atherosclerosis by regulating TGF-β/Smad3 pathway in 5/6 nephrectomy ApoE(−/−) mice
BACKGROUND: Hydrogen sulfide (H(2)S) has been shown to inhibit the atherosclerosis development and progression. It is produced by cystathionine γ-lyase (CSE) in the cardiovascular system. In our previous study, it has been shown that CSE/H(2)S system plays a significant role in the changes of uremic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716493/ https://www.ncbi.nlm.nih.gov/pubmed/33276745 http://dx.doi.org/10.1186/s12882-020-02183-z |