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Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova

Despite all recent advances in the diagnosis and treatment of hepatitis C virus infection, the incidence remains high, motivating the present study to improve the prognosis of the disease through early diagnosis of asymptomatic patients with possible detectable risk factors. The aim of this study is...

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Autores principales: BUTARU, ANCA ELENA, DOICA, IRINA PAULA, GHEONEA, DAN IONUŢ, ROGOVEANU, ION, DICULESCU, MIRCEA, OANCEA, CARMEN NICOLETA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716757/
https://www.ncbi.nlm.nih.gov/pubmed/33304621
http://dx.doi.org/10.12865/CHSJ.46.03.01
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author BUTARU, ANCA ELENA
DOICA, IRINA PAULA
GHEONEA, DAN IONUŢ
ROGOVEANU, ION
DICULESCU, MIRCEA
OANCEA, CARMEN NICOLETA
author_facet BUTARU, ANCA ELENA
DOICA, IRINA PAULA
GHEONEA, DAN IONUŢ
ROGOVEANU, ION
DICULESCU, MIRCEA
OANCEA, CARMEN NICOLETA
author_sort BUTARU, ANCA ELENA
collection PubMed
description Despite all recent advances in the diagnosis and treatment of hepatitis C virus infection, the incidence remains high, motivating the present study to improve the prognosis of the disease through early diagnosis of asymptomatic patients with possible detectable risk factors. The aim of this study is to identify HCV infection in a disadvantaged population before the onset of symptoms and guide to specialized services for initiation of antiviral therapy, thus adhering to the WHO goal of elimination the infection. Materials and Methods: In the first two weeks after the start of the study, 320 patients with detectable risk factors for HCV were tested using rapid tests, in a southwestern city of Romania, Orşova, with the participation of four doctors, via Family Medicine Offices. Results: As a percentage, the amount of detection based on rapid tests was 2.5%, the positive results have apparently been achieved exclusively among female subjects. All patients have been informed about the result and included in the diagnostic trial, where they were fully evaluated to determine if they were eligible for therapy. Conclusions. Population screening contributes to the diagnosis and elimination of an underdiagnosed pathology, in a disadvantaged area with limited access to medical care. The positive feedback that has been received in just a few weeks after its beginning, once again has motivated to emphasis the population screening, with real considerations on the possibility of expanding this program on a large scale.
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spelling pubmed-77167572020-12-09 Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova BUTARU, ANCA ELENA DOICA, IRINA PAULA GHEONEA, DAN IONUŢ ROGOVEANU, ION DICULESCU, MIRCEA OANCEA, CARMEN NICOLETA Curr Health Sci J Original Paper Despite all recent advances in the diagnosis and treatment of hepatitis C virus infection, the incidence remains high, motivating the present study to improve the prognosis of the disease through early diagnosis of asymptomatic patients with possible detectable risk factors. The aim of this study is to identify HCV infection in a disadvantaged population before the onset of symptoms and guide to specialized services for initiation of antiviral therapy, thus adhering to the WHO goal of elimination the infection. Materials and Methods: In the first two weeks after the start of the study, 320 patients with detectable risk factors for HCV were tested using rapid tests, in a southwestern city of Romania, Orşova, with the participation of four doctors, via Family Medicine Offices. Results: As a percentage, the amount of detection based on rapid tests was 2.5%, the positive results have apparently been achieved exclusively among female subjects. All patients have been informed about the result and included in the diagnostic trial, where they were fully evaluated to determine if they were eligible for therapy. Conclusions. Population screening contributes to the diagnosis and elimination of an underdiagnosed pathology, in a disadvantaged area with limited access to medical care. The positive feedback that has been received in just a few weeks after its beginning, once again has motivated to emphasis the population screening, with real considerations on the possibility of expanding this program on a large scale. Medical University Publishing House Craiova 2020 2020-09-30 /pmc/articles/PMC7716757/ /pubmed/33304621 http://dx.doi.org/10.12865/CHSJ.46.03.01 Text en Copyright © 2014, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Original Paper
BUTARU, ANCA ELENA
DOICA, IRINA PAULA
GHEONEA, DAN IONUŢ
ROGOVEANU, ION
DICULESCU, MIRCEA
OANCEA, CARMEN NICOLETA
Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova
title Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova
title_full Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova
title_fullStr Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova
title_full_unstemmed Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova
title_short Preliminary Results of the Micro-Elimination Project of Hepatitis C in a Disadvantaged Town in South-West of Romania-Orşova
title_sort preliminary results of the micro-elimination project of hepatitis c in a disadvantaged town in south-west of romania-orşova
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716757/
https://www.ncbi.nlm.nih.gov/pubmed/33304621
http://dx.doi.org/10.12865/CHSJ.46.03.01
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